Arini Arini, Djusiana Eka Cesarria, Haryati Haryati


Background: Depo Provera is the most used injecting contraception in Indonesia and it given every 3 months. Injectable contraception of Depo Provera has a high effectiveness, but there are some side effects that caused by prolonged use, one of which is a disturbed pattern of menstruation. Objectives: The aimed of this research was to analyze the effect of prolonged use of Depo Provera contraception to menstrual pattern changes on fertile age women in Kendari City. Methods: The type of this research was an analytic survey by using cross sectional design. The study was conducted in August 2017 until January 2018 at all community health centers in Kendari. The instrument that used in this research was a questionnaire about the menstrual pattern. The sampling technique used was purposive sampling and the total samples were 380 respondents. Data analysis used by univariate analysis and bivariate analysis with chi square statistic test. Results : The results showed that the use of Depo Provera contraception old and new categories by respondents of fertile age women who experienced menstrual pattern changes amounted to 351 respondents (92,37%), with chi square statistical test obtained p value = 0.047, then statistically showed that there was an effect of prolonged use of Depo Provera contraception to the change of menstrual patterns, including menstrual cycle changes as much as 351 respondents (p value = 0.047), menstrual duration changes as much as 287 respondents (p value = 0.038), and abnormal menstrual blood count as much 297 respondents (p value = 0.043). Hormon progesterone that contained in Depo Provera concentrations will lead histologic changes of the endometrium to endometrial atrophy that will affect the pattern of menstruation. Conclusions:  The conclusion of this study that there was a significant effect of prolonged use of Depo Provera contraception to the menstrual pattern changes on fertile age women in Kendari City.



Depo Provera, Fertile Age Women, Menstrual Pattern, Prolonged Use

Full Text:



Arantriwardhani. (2010). The Effect of Depo Provera Contraception Against The Occurrence of Menstrual Abnormality at Ngoresan Surakarta Health Center.

Badan Pusat Statistik. (2010). Population of Indonesia: Results of Population Census 2010. Badan Pusat Statistik, Jakarta.

Badan Pusat Statistik Provinsi Sultra. (2015). Southeast Sulawesi in Figure Year 2015. (Bidang Integrasi Pengolahan dan Diseminasi Statistik, Ed.). Kendari: Badan Pusat Statistik Provinsi Sulawesi Tenggara.

David, P. S., Boatwright, E. A., Beverly S. Tozer, Verma, D. P., Blair, J. E., Mayer, A. P., & Files, J. A. (2006). Hormonal Contraception Update (Vol. 85259, pp. 949–955). Mayoclinic Proceedings.

Dinas Kesehatan Kota Kendari. (2016). Proportion of Contraception Aceptors Based on Type of Contraception, Districts, and Public Health Centre 2016. Kendari.

Dinas Kesehatan Provinsi Sultra. (2016). The Proportion of Contraception Acceptors Based on Type of Contraception in Southeast Sulawesi 2016. Kendari.

Hartanto, H. (2004). Family Planning and Contraception (Fifth). Jakarta: Sinar Harapan Library.

Irmawati. (2012). Factors that Influences the Use of Hormonal Contraceptives on Family Planning Acceptor at Samata Health Center of Sombo Opu District.

Kemenkes RI. (2016). Indonesian Health Profile Year 2015. (D. Budijanto, Yudianto, B. Hardhana, & T. A. Soenardi, Eds.). Kementerian Kesehatan Republik Indonesia.

Marmi. (2015). Family Planning Teaching Book. Yogyakarta: Student Library.

Panuntun, S., Wilopo, S. A., & Kurniawati, L. (2009). Relationship between Access to Family Planning with Election of Hormonal and Non Hormonal Contraception in Purworejo District. Berita Kedokteran Masyarakat, 25(2), 88–95.

Prawirohardjo, S. (2014). Science of Gynecology (Third). Bina Pustaka Foundation Sarwono Prawirohardjo.

Suryati. (2013). Effect of Contraceptive Injection on Menstrual Cycles on Fertile Age Couples in Private Practice Midwife Heramuliati Padang Tiji Sub-district Pidie Regency. Retrieved from

Veisi, F., & Zangeneh, M. (2013). Comparison of Two Different Injectable Contraceptive Methods: Depo-medroxy Progesterone Acetate (DMPA) and Cyclofem. Journal of Family and Reproductive Health, 109–113.


  • There are currently no refbacks.