Tri Antika Rizki Kusuma Putri, I Made Kariasa, Debby Dahlia


Background: Medication adherence remains public health attention which may affect clinical outcomes and quality of life of patients with Myasthenia Gravis (MG). However, studies on medication adherence, and its association with clinical outcome and quality of life been poorly characterized among patients with MG. Objectives: The study aimed to explore the relationship between medication adherence with clinical outcome and quality of life of patients with MG. Methods: A cross-sectional study of patients with myasthenia gravis at 75 patients with MG was conducted at the foundation of MG in Indonesia. Data were collected from May to October 2016. A purposive sampling technique was used to select subject based on inclusion criteria. MG-PRO instrument was used to measure the quality of life and Barthel index to measure functional ability. Also, to evaluate the clinical outcome, Myasthenia Gravis Foundation of America (MGFA) classification was applied. All data were analyzed using a parametric test, namely independent t-test. Results: The results of this study showed a significant association between medication adherence with clinical outcome (p=0.000) and quality of life (p=0.048) among patients with MG. Conclusions: Medication adherence was associated with clinical outcome and quality of life of patients with MG. Nurse and other healthcare professionals need to design an intervention to improve the adherence to medication, not only during hospitalization but also in the rehabilitation phase to prevent from a myasthenia crisis.



adherence, clinical outcome, myasthenia gravis, quality of life

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