THE INFLUENCE OF NUTRITIONAL STATUS AND CANCER-RELATED FATIGUE (CRF) ON QUALITY OF LIFE IN CANCER SURVIVORS

Ni Putu Wulan Purnama Sari

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Background: People who are live with cancer often experience malnutrition due to the disease mechanism, host response towards tumor, and side effect of anti-cancer therapy. Nutrient or energy deficiency added by some other contributing factors may result in CRF that potentially decrease quality of life (QOL). Objectives: This study aimed to analyze the influence of nutritional status and CRF on QOL in cancer survivors. Methods: This is a cross-sectional study.  Population was all cancer patients in the district of Rangkah, Gading, and Pacarkeling, Surabaya. Sample size was 129. Total sampling was applied. Instrument of PG-SGA, FSI, and QOL-CS were used for data collection. Simple and multiple linear regression test was used in data analysis (α<.05). Ethical clearance was issued. Results: 58 breast cancer, 47 cervical cancer, and 24 other cancer survivors participated in this study. Majority was married woman, 51-50 years old, housewife, Islam, Javanese, lives with spouse, GDP less than minimum wage, have cancer for more than four years, and already had a surgery. Most respondents were well-nourished, experienced mild CRF, and had moderate QOL. Nutritional status influenced CRF and QOL significantly by 23.80% and 9.20% respectively, while CRF influenced QOL significantly by 53.60% (@ p=.000). Nutritional status together with CRF could influence QOL significantly by 54% (p=.000). Conclusions: Nutritional status and CRF influence QOL significantly in cancer survivors, in which CRF has greater influence than nutritional status. Poor nutritional status along with severe CRF is highly potential for lowering QOL significantly.


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cancer, cancer-related fatigue, nutritional status, quality of life.

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